THIS WEEKS LATEST LEARNINGS
Cool stuff absolutely nobody knows.
THE FAT LOSS ISSUE
Immune Cell Stops
Weight Regain
A type of immune cell called CD7+ seems to accumualte in bone marrow in humans during weight loss. These immune cells seem to have what could be termed "metabolic memory". They have the power to migrate into body fat and secrete a key protein that turns up brown fat thermogenesis, effectively inhibiting weight regain.
The problem seems to be they go to sleep post fat loss. In technical terms, they enter a quiescent state. The quiescent state predisposes weight regain. Stimulation of a specific kinase (FLT3L) seems to turn up these immune cells and prevents weight regain. This research substantiates an immune centric approach to the post fat loss phase, where targeted activation of key immune cells can help prevent weight regain.
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DDT derivative
accumulates in fat
tissue, stunts fat
loss.
A derivative of the pesticide DDT known as DDE, accumulates in fat tissue. Upon fat loss, DDE is released into the serum. A recent study of 63 teens over 5 years showed that during fat loss, a lower exposure to DDE resulted in greater fat loss and less weight regain.
The primary source of DDT exposure is animal fat, meat and particularly fish from waters contaminated with DDT. Mothers can also expose children to DDE via breastmilk if mother has high levels in her body.
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Menthol and Garlic trigger visceral fat release via TRPV3
v
Transient receptor potential vanilloid is a protein that regulates ion channels to control calcium flux in cells. A promising new mice study shows TRPV3 enhanced lipolysis in visceral fat by turning up a key fat loss enzyme, adipocyte triglyceride lipase (ATGL).
As it turns out, menthols seem to turn up TRPV3. In addition, other compounds like garlic and camphor also turn up TRPV3. Those of you who read the Immunity Code are familiar with the combo of cold + menthol for fat burning.
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It seems kids need their carbs. A new study examining the impact of lunch on fat oxidation during exercise later in the day revealed something interesting - carbs beat protein!
Although a small study, comprised of only 12 male teens, the surprising result suggests that carbs have a key role in maximal exercise performance and body composition. Teens who subbed out protein for carbs had greater fat oxidation, ca, better hormonal appetite, and reduced post-exercise energy intake.
Carbs at Lunch Increased Fat Oxidation
More Than Protein in
Teens
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